Acetic Anhydride → HCID 20145181, Verbindung

HRID 648640Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 648640
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([N:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)=[C:6]([CH:8]([CH:10]([C:20]([NH2:22])=[O:21])[C:11]2[CH:19]=[CH:18][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=2)[CH3:9])[CH:7]=1.[C:29](OC(=O)C)(=[O:31])[CH3:30]>>[C:29]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([N:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)=[C:6]([CH:8]([CH:10]([C:20]([NH2:22])=[O:21])[C:11]2[CH:19]=[CH:18][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=2)[CH3:9])[CH:7]=1)(=[O:31])[CH3:30]

Komponenten

3

Edukt 2

HCID 7918Acetic AnhydrideHCID 20145241HCID 20145241, Verbindung

Produkt 1

HCID 20145181HCID 20145181, Verbindung

Versuchsvorschrift

An amount of 0.10 gm (0.262 m mol) of 4-[(1-(5-amino-2-piperidino-phenyl)-ethyl)-aminocarbonylmethyl]-benzoic acid in 1 ml of acetic anhydride was stirred for six hours at 20° C., evaporated in vacuo, and distilled off several times with toluene, and the evaporation residue was recrystallized from ether.

Aufarbeitung

  1. customevaporated in vacuo
  2. distillationdistilled off several times with toluene
  3. customthe evaporation residue was recrystallized from ether

Quellen und Nachweise

ORD-Eintrag
ord-8bf896ff200b4485b23d43d618bb3e6c
Quelldatensatz
uspto-grants-1988_04
Patentnummer
US04735959

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