Acetic Acid → HCID 178468982, Verbindung

HRID 648901

Reaktionsgleichung

Reaktionsgleichung von HRID 648901
C(C1C=C[C:9]([NH:12][NH:13][C:14]([NH2:16])=[S:15])=CC=1)(OCC)=O.[CH:17]([O-:22])([O-])[O:18][CH2:19][CH3:20].C(O)(=O)C.[CH3:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]>>[C:17]([C:29]1[CH:28]=[CH:27][C:32]([N:16]2[CH:9]=[N:12][N:13]=[C:14]2[SH:15])=[CH:31][CH:30]=1)([O:18][CH2:19][CH3:20])=[O:22]

Komponenten

5

Edukt 4

HCID 176Acetic AcidHCID 8058HexaneHCID 197457524-EthoxycarbonylphenylthiosemicarbazideHCID 53630039Ethylorthoformate

Produkt 1

HCID 178468982HCID 178468982, VerbindungAusbeute 75,9 %

Reaktionsbedingungen

Temperatur
120 °C

Versuchsvorschrift

A mixture of 13.2 g of (4-carboethoxyphenyl)thiosemicarbazide, 52.8 ml of ethyl orthoformate, and 3.3 g of acetic acid was stirred for 2 hours at 120° C. After cooling the mixture to room temperature, hexane was added to the mixture and crystals thus formed were collected by filtration and recrystallized from ethanol to provide 10.4 g of 1-(4-carboethoxyphenyl)-2-mercapto-1,3,4-triazole. The yield was 75.9% and the melting point was 194°-196° C.

Aufarbeitung

  1. temperatureAfter cooling the mixture to room temperature
  2. customthus formed
  3. filtrationwere collected by filtration
  4. customrecrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-17ebcef140f64fa1a98937d7285ff0b4
Quelldatensatz
uspto-grants-1988_04
Patentnummer
US04737452

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