1H-Benzimidazole, 5,6-dichloro-1-ethyl-2-methyl- → HCID 178462747, Verbindung

HRID 649493

Reaktionsgleichung

Reaktionsgleichung von HRID 649493
[Cl:1][C:2]1[C:13]([Cl:14])=[CH:12][C:5]2[N:6]([CH2:10][CH3:11])[C:7]([CH3:9])=[N:8][C:4]=2[CH:3]=1.Cl[CH2:16][CH2:17][NH:18][S:19]([CH3:22])(=[O:21])=[O:20]>C1(OC)C=CC=CC=1>[Cl-:1].[Cl:1][C:2]1[C:13]([Cl:14])=[CH:12][C:5]2[N+:6]([CH2:10][CH3:11])=[C:7]([CH3:9])[N:8]([CH2:16][CH2:17][NH:18][S:19]([CH3:22])(=[O:21])=[O:20])[C:4]=2[CH:3]=1

Komponenten

4

Edukt 2

HCID 767171H-Benzimidazole, 5,6-dichloro-1-ethyl-2-methyl-HCID 89092N-(2-Chloroethyl)methanesulphonamide

Produkt 1

HCID 178462747HCID 178462747, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7519AnisoleLösungsmittel

Reaktionsbedingungen

Temperatur
150 °C

Versuchsvorschrift

22.9 g (0.1 mol) of 5,6-dichloro-1-ethyl-2-methylbenzoimidazole and 23.6 g (0.15 mol) of N-(2-chloroethyl)methanesulfonamide were put into a 200-ml three-necked flask equipped with a stirrer and heated with stirring for 2 hours on an oil bath which had been heated to a temperature of 150° C. Then, 20 ml of anisole was added to the mixture. The mixture was then allowed to cool to room temperature with stirring. The resulting crystals were filtered off, washed with acetone and isopropanol, and dried.

Aufarbeitung

  1. customequipped with a stirrer
  2. temperatureheated
  3. temperatureto cool to room temperature
  4. stirringwith stirring
  5. filtrationThe resulting crystals were filtered off
  6. washwashed with acetone and isopropanol
  7. customdried

Quellen und Nachweise

ORD-Eintrag
ord-a56c3e55fb414f519a9b494eeb94be17
Quelldatensatz
uspto-grants-1988_04
Patentnummer
US04740455

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