Ethanol → 1-(Naphthalen-2-yl)ethan-1-amine

HRID 649875

Reaktionsgleichung

Reaktionsgleichung von HRID 649875
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]([NH:13]C=O)[CH3:12].C(O)C.[OH-].[Na+]>O>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]([NH2:13])[CH3:12]

Komponenten

5

Edukt 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 18543124N-[1-(2-Naphthalenyl)ethyl]formamide

Produkt 1

HCID 38571451-(Naphthalen-2-yl)ethan-1-amineAusbeute 98,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of N-(1-naphthalen-2-yl-ethyl)-formamide (1.12 g), ethanol (10 mL) and 5 N sodium hydroxide (10 mL) is heated at reflux for 1 hour. The solution is cooled, poured into water and extracted with ether. The ether solution is dried with anhydrous potassium carbonate, filtered and concentrated to give the product (0.95 g) as a pale yellow oil.

Aufarbeitung

  1. temperatureis heated
  2. temperatureat reflux for 1 hour
  3. temperatureThe solution is cooled
  4. extractionextracted with ether
  5. dry with materialThe ether solution is dried with anhydrous potassium carbonate
  6. filtrationfiltered
  7. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-8a5c8f9029dc4da9a4345e7fb34c6271
Quelldatensatz
uspto-grants-2001_08
Patentnummer
US06271236B1

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