Hydrogen Peroxide → HCID 13911126, Verbindung

HRID 651948

Reaktionsgleichung

Reaktionsgleichung von HRID 651948
[OH:1][C:2]([CH2:5][CH2:6][CH2:7][C@H:8]([C@@H:10]1[C@:27]2([CH3:28])[C@H:13]([C@H:14]3[C@H:24]([CH2:25][CH2:26]2)[C@:22]2([CH3:23])[C:17](=[CH:18][C:19](=[O:29])[CH:20]=[CH:21]2)[CH:16]=[CH:15]3)[CH2:12][CH2:11]1)[CH3:9])([CH3:4])[CH3:3].[OH-:30].[K+].OO>C(O)C.O>[O:30]1[C@H:20]2[C:19](=[O:29])[CH:18]=[C:17]3[C@:22]([CH3:23])([C@@H:21]12)[C@@H:24]1[C@H:14]([C@H:13]2[C@:27]([CH3:28])([CH2:26][CH2:25]1)[C@@H:10]([C@H:8]([CH3:9])[CH2:7][CH2:6][CH2:5][C:2]([OH:1])([CH3:3])[CH3:4])[CH2:11][CH2:12]2)[CH:15]=[CH:16]3

Komponenten

6

Edukt 3

HCID 784Hydrogen PeroxideHCID 14797Potassium HydroxideHCID 2279738725-Hydroxycholesta-1,4,6-trien-3-one

Produkt 1

HCID 13911126HCID 13911126, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

The trienone from (a) (1.3 gms) in ethanol (50 mls) was treated with 10% aqueous potassium hydroxide (0.5 ml) and 30% aqueous H2O2 (3 ml). After storage overnight at room temperature, the solution was diluted with water and the solid product collected. Recrystallization from aqueous methanol gave the title compound which after one further crystallization had melting point 162°-163°.

Aufarbeitung

  1. customthe solid product collected
  2. customRecrystallization from aqueous methanol

Quellen und Nachweise

ORD-Eintrag
ord-c0d60886cd6b4abc8e6870ceca398957
Quelldatensatz
uspto-grants-1987_06
Patentnummer
US04670190

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