4,4'-Dihydroxybiphenyl → HCID 19887240, Verbindung

HRID 654417Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 654417
Br[CH2:2][CH2:3][O:4][CH2:5][CH2:6][CH2:7][CH3:8].[OH:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=2)=[CH:12][CH:11]=1.C(=O)([O-])[O-].[K+].[K+]>C(#N)C>[CH2:5]([O:4][CH2:3][CH2:2][O:9][C:10]1[CH:11]=[CH:12][C:13]([C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=2)=[CH:14][CH:15]=1)[CH2:6][CH2:7][CH3:8]

Komponenten

5

Edukt 3

HCID 71124,4'-DihydroxybiphenylHCID 11430Potassium CarbonateHCID 1387612-Butoxyethyl bromide

Produkt 1

HCID 19887240HCID 19887240, VerbindungAusbeute 20 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

One gram (5.5 millimoles) of 1-bromo-2-butoxyethane was combined with 5.5 grams (30 millimoles) of 4,4'-dihydroxybiphenyl in 75 mls. of acetonitrile. To the reaction mixture were added 8.3 grams (60 millimoles) of finely ground potassium carbonate. Stirring was begun and the reaction mixture was brought to reflux and maintained for 48 hours. The reaction product was filtered, washed with acetonitrile and evaporated for removal of solvent. The product was passed through a silica gel chromatographic column using dichloromethane eluent, for recovery of 0.25 gram (20% yield) of a biphenol ether compound having the following formula confirmed by TLC, IR and mass spectral analyses: ##STR26##

Aufarbeitung

  1. temperatureto reflux
  2. temperaturemaintained for 48 hours
  3. filtrationThe reaction product was filtered
  4. washwashed with acetonitrile
  5. customevaporated for removal of solvent

Quellen und Nachweise

ORD-Eintrag
ord-cc03d9841e7b41ffb2eb7a7d00bd189c
Quelldatensatz
uspto-grants-1992_07
Patentnummer
US05132041

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