Acetic Anhydride → HCID 19886039, Verbindung

HRID 655051Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 655051
[CH3:1][O:2][C:3]1[CH:37]=[CH:36][C:6]([CH2:7][O:8][C:9]2[CH:10]=[C:11](C(OCC3C=CC=CC=3)(O)C)[CH:12]=[CH:13][C:14]=2[O:15][CH2:16][C:17]2[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=2)=[CH:5][CH:4]=1.[C:38](OC(=O)C)(=[O:40])[CH3:39]>N1C=CC=CC=1>[CH3:24][O:23][C:20]1[CH:21]=[CH:22][C:17]([CH2:16][O:15][C:14]2[C:9]([O:8][CH2:7][C:6]3[CH:36]=[CH:37][C:3]([O:2][CH3:1])=[CH:4][CH:5]=3)=[CH:10][CH:11]=[CH:12][C:13]=2[CH:38]([OH:40])[CH3:39])=[CH:18][CH:19]=1

Komponenten

4

Edukt 2

HCID 7918Acetic AnhydrideHCID 67742855HCID 67742855, Verbindung

Produkt 1

HCID 19886039HCID 19886039, VerbindungAusbeute 91,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

To an ice cold solution of α-chloro-3,4-dihydroxypropiophenone (2) (1.0 g; 4.98 mMol.) in pyridine (3 ml) is added acetic anhydride (1.2 ml) After 1.5 hours at room temperature, the reaction mixture is concentrated under reduced pressure. The residue is dissolved in chloroform, washed with water, dried, and concentrated under reduced pressure to give α-chloro-2,3-diacetoxypropiopheonen (3) (1.3 g).

Aufarbeitung

  1. concentrationthe reaction mixture is concentrated under reduced pressure
  2. dissolutionThe residue is dissolved in chloroform
  3. washwashed with water
  4. customdried
  5. concentrationconcentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-b20ab1833c8e4b77a941b5b82cc494d5
Quelldatensatz
uspto-grants-1992_07
Patentnummer
US05134138

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