Benzyl Bromide → 8-(Benzyloxy)quinoline-2-carbaldehyde
Reaktionsgleichung
[OH:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[C:9]([CH3:12])[CH:8]=[CH:7]2.[CH2:13](Br)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[Se](=O)=[O:22]>>[CH2:13]([O:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[C:9]([CH:12]=[O:22])[CH:8]=[CH:7]2)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1Komponenten
4
Versuchsvorschrift
The title compound was prepared from 8-hydroxy-2-methylquinoline (6d), benzyl bromide, and selenium dioxide using methods as described in the literature for similar compounds (Buchi et al., 1956) in 35% yield.
Quellen und Nachweise
- ORD-Eintrag
- ord-b4fe30d4def747eca6f38b9193a0fa2b
- Quelldatensatz
- uspto-grants-2011_12
- Patentnummer
- US08071620B2
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