Dimethylformamide dimethyl acetal → N-[1-Dimethylaminomethylidene]-3-methylsulfanylbenzamide

Beteiligte Stoffe

Reaktionsschritte

8.5 g of 3-methylsulfanylbenzamide and 18 ml of dimethylformamide dimethyl acetal were heated at 120° C. while the formed methanol was eliminated by distillation. After heating for 3 h, the volatiles were removed in vacuo. The crude product was purified by flash chromatography (300 g silica gel; DCM/MOH, gradient from 100:0 to 95:5). 8 g of the title compound were obtained as an oil.

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