Sodium Hydroxide → Ampicillin Sodium

HRID 66053Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 66053
[CH3:1][C:2]1([CH3:24])[S:6][C@@H:5]2[C@H:7]([NH:10][C:11]([C@H:13]([NH2:20])[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[O:12])[C:8](=[O:9])[N:4]2[C@H:3]1[C:21]([OH:23])=[O:22].O.O.O.[OH-].[Na+:29]>O>[CH3:1][C:2]1([CH3:24])[S:6][C@@H:5]2[C@H:7]([NH:10][C:11]([C@H:13]([NH2:20])[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[O:12])[C:8](=[O:9])[N:4]2[C@H:3]1[C:21]([O-:23])=[O:22].[Na+:29]

Komponenten

4

Edukt 2

HCID 14798Sodium Hydroxide2×HCID 23565Ampicillin Trihydrate

Produkt 1

HCID 23663979Ampicillin Sodium

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A suspension of 24.18 gm (60 millimols) of ampicillin trihydrate in 140 ml of water was admixed with 55.2 ml of an aqueous 1N sodium hydroxide solution (8% less than equimolar amount of NaOH) in the manner and under the conditions described in Example 1, and the sodium ampicillin was isolated in exactly the same manner as in Example 1.

Quellen und Nachweise

ORD-Eintrag
ord-177c8f38f14b4e4d99132f91365c0976
Quelldatensatz
uspto-grants-1978_12
Patentnummer
US04130558

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