Phosphorus pentachloride → N-(3,4-dichlorostyrylsulfonyl)-3,4-dimethoxybenzimidoyl chloride

HRID 66205

Reaktionsgleichung

Reaktionsgleichung von HRID 66205
[Cl:1][C:2]1[CH:3]=[C:4]([CH:23]=[CH:24][C:25]=1[Cl:26])[CH:5]=[CH:6][S:7]([NH:10][C:11](=O)[C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([O:20][CH3:21])[CH:13]=1)(=[O:9])=[O:8].P(Cl)(Cl)(Cl)(Cl)[Cl:28]>C1C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[C:4]([CH:23]=[CH:24][C:25]=1[Cl:26])[CH:5]=[CH:6][S:7]([N:10]=[C:11]([Cl:28])[C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([O:20][CH3:21])[CH:13]=1)(=[O:9])=[O:8]

Komponenten

4

Edukt 2

HCID 24819Phosphorus pentachlorideHCID 54226549N-(3,4-dichlorostyrylsulfonyl)-3,4-dimethoxybenzamide

Produkt 1

HCID 54107493N-(3,4-dichlorostyrylsulfonyl)-3,4-dimethoxybenzimidoyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel

Versuchsvorschrift

A suspension of N-(3,4-dichlorostyrylsulfonyl)-3,4-dimethoxybenzamide (8.3 g., 0.02 mole) in 100 ml. of dry benzene is stirred and refluxed with phosphorus pentachloride (4.6 g., 0.022 mole) for a period of 1.5 hr. providing a clear solution which is concentrated under reduced pressure. Benzene is added to the residue and evaporated. The benzene treatment is repeated several times and the residue thus obtained triturated with isopropyl ether provides a quantitative yield of N-(3,4-dichlorostyrylsulfonyl)-3,4-dimethoxybenzimidoyl chloride, m.p. 120°-125° C.

Aufarbeitung

  1. customproviding a clear solution which
  2. concentrationis concentrated under reduced pressure
  3. additionBenzene is added to the residue
  4. customevaporated
  5. customthe residue thus obtained
  6. customtriturated with isopropyl ether

Quellen und Nachweise

ORD-Eintrag
ord-bd2596347e3e4e34b477f70ffc079fd0
Quelldatensatz
uspto-grants-1978_12
Patentnummer
US04130663

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