Selenium Dioxide → 2-Ethoxyphenylglyoxal

HRID 66324Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 66324
C([O:3][CH2:4][C:5]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:6])C.[Se](=O)=O.[O:16]1CCO[CH2:18][CH2:17]1>O.C(OCC)(=O)C>[CH2:17]([O:16][C:12]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:5]([CH:4]=[O:3])=[O:6])[CH3:18]

Komponenten

6

Edukt 3

HCID 24007Selenium DioxideHCID 312751,4-DioxaneHCID 1398412-Ethoxy-1-phenylethan-1-one

Produkt 1

HCID 227549162-Ethoxyphenylglyoxal

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

2 g of 2-ethoxyacetophenone are dissolved in 20 ml of dioxane, and a solution of 2 g of selenium dioxide in one ml of water is added thereto. The solution is refluxed for 10 hours. After the reaction, insoluble materials are removed by filtration, and the filtrate is concentrated. The residue thus obtained is dissolved in ethyl acetate. The ethyl acetate solution is washed with water and then with an aqueous sodium bicarbonate solution and water. Then, said solution is dried and evaporated to remove solvent. 2.1 g of 2-ethoxyphenylglyoxal are obtained as a crude oil.

Aufarbeitung

  1. temperatureThe solution is refluxed for 10 hours
  2. customAfter the reaction, insoluble materials
  3. customare removed by filtration
  4. concentrationthe filtrate is concentrated
  5. customThe residue thus obtained
  6. washThe ethyl acetate solution is washed with water
  7. customis dried
  8. customevaporated
  9. customto remove solvent

Quellen und Nachweise

ORD-Eintrag
ord-74c949b65bbb45b78134c4849088b0f2
Quelldatensatz
uspto-grants-1978_12
Patentnummer
US04131686

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