6-Methyl-2-nitropyridin-3-ol → 2-Amino-6-methylpyridin-3-ol
Reaktionsgleichung
[OH:1][C:2]1[C:3]([N+:9]([O-])=O)=[N:4][C:5]([CH3:8])=[CH:6][CH:7]=1>[Pd].CO>[NH2:9][C:3]1[C:2]([OH:1])=[CH:7][CH:6]=[C:5]([CH3:8])[N:4]=1Komponenten
4
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
3-Hydroxy-6-methyl-2-nitropyridine (3.5 g.) in 75 ml. of methanol was reduced over 1 g. of 5% palladium-on-carbon catalyst. The catalyst was removed by filtration and the filtrate was concentrated to dryness to give 2-amino-3-hydroxy-6-methylpyridine which was used directly in the next step.
Aufarbeitung
- customThe catalyst was removed by filtration
- concentrationthe filtrate was concentrated to dryness
Quellen und Nachweise
- ORD-Eintrag
- ord-4289872c8b854b6d8388299f54433d7b
- Quelldatensatz
- uspto-grants-1978_12
- Patentnummer
- US04131677
Notizen zur Reaktion
Wird geladen…