3-Methoxy-2-methyl-6-nitropyridine → 5-Methoxy-6-methylpyridin-2-amine
Reaktionsgleichung
[CH3:1][O:2][C:3]1[C:4]([CH3:12])=[N:5][C:6]([N+:9]([O-])=O)=[CH:7][CH:8]=1>[Pd].CO>[NH2:9][C:6]1[N:5]=[C:4]([CH3:12])[C:3]([O:2][CH3:1])=[CH:8][CH:7]=1Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
3-Methoxy-2-methyl-6-nitropyridine (0.317 g.) in 20 ml. of methanol, was hydrogenated over 0.1 g. of 5% palladium-on-carbon catalyst. The catalyst was removed by filtration and the filtrate was concentrated to dryness to give 6-amino-3-methoxy-2-methylpyridine, which was used directly in the next step.
Aufarbeitung
- customThe catalyst was removed by filtration
- concentrationthe filtrate was concentrated to dryness
Quellen und Nachweise
- ORD-Eintrag
- ord-eec27c9e560f49c7b7304c07e17a30ed
- Quelldatensatz
- uspto-grants-1978_12
- Patentnummer
- US04131677
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