Potassium Carbonate → HCID 178432777, Verbindung

HRID 66720

Reaktionsgleichung

Reaktionsgleichung von HRID 66720
[Cl:1][C:2]([Cl:7])([Cl:6])[C:3]([NH2:5])=[NH:4].C(=O)([O-])[O-].[K+].[K+].[Cl:14][CH:15]([C:21]([CH3:23])=O)[C:16](OCC)=[O:17]>O>[Cl:14][C:15]1[C:16]([OH:17])=[N:4][C:3]([C:2]([Cl:7])([Cl:6])[Cl:1])=[N:5][C:21]=1[CH3:23]

Komponenten

5

Edukt 3

HCID 11430Potassium CarbonateHCID 11858Ethyl 2-chloroacetoacetateHCID 356082,2,2-Trichloroethanimidamide

Produkt 1

HCID 178432777HCID 178432777, VerbindungAusbeute 31 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 30.0 g (0.18 mole) trichloroacetamidine, 25.2 g (0.18 mole) potassium carbonate, 30.3 g (0.18 mole) ethyl 2-chloroacetoacetate, and 300 ml water was stirred 18 hours. The aqueous solution was decanted from heavier tars and acidified with hydrochloric acid. The precipitate that was formed was filtered, washed, and dried to give 14.7 g (31% yield; mp 130°-145° C.) of crude product. An analytical sample recrystallized from cyclohexane had mp 156°-157° C. The structure was confirmed via infrared and elemental analysis.

Aufarbeitung

  1. customThe aqueous solution was decanted from heavier tars
  2. customThe precipitate that was formed
  3. filtrationwas filtered
  4. washwashed
  5. customdried
  6. customto give 14.7 g (31% yield; mp 130°-145° C.) of crude product
  7. customAn analytical sample recrystallized from cyclohexane

Quellen und Nachweise

ORD-Eintrag
ord-7fa793f8618c41de8b007b91799daca8
Quelldatensatz
uspto-grants-1982_08
Patentnummer
US04343803

Verknüpfte Notizen

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