Itaconic acid → trans-N-Decyl-2-[4-(4-carboxy-2-oxo-pyrrolidino)-phenyl]cyclopropanecarboxamide
Reaktionsgleichung
[CH2:1]([NH:11][C:12]([C@@H:14]1[CH2:16][C@H:15]1[C:17]1[CH:22]=[CH:21][C:20]([NH2:23])=[CH:19][CH:18]=1)=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[C:24]([OH:32])(=[O:31])[C:25]([CH2:27][C:28](O)=[O:29])=[CH2:26]>>[CH2:1]([NH:11][C:12]([C@@H:14]1[CH2:16][C@H:15]1[C:17]1[CH:22]=[CH:21][C:20]([N:23]2[CH2:26][CH:25]([C:24]([OH:32])=[O:31])[CH2:27][C:28]2=[O:29])=[CH:19][CH:18]=1)=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]Komponenten
3
Versuchsvorschrift
The title compound was prepared from trans-N-decyl-2-(4-aminophenyl)cyclopropanecarboxamide and itaconic acid, substantially according to the procedure of Example 10. It was recrystallized twice from ethanol to give a 47% yield of material having a melting point of 214°-215° C. The infrared spectrum (KBr disc) showed absorptions at 3280, 3125, 1680 and 1625 cm-1.
Aufarbeitung
- customIt was recrystallized twice from ethanol