Sodium Chloride → HCID 20529096, Verbindung

HRID 66827Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 66827
C(OC([CH:6]1[CH2:33][CH2:32][CH2:31][N:9]2[C:10]3[C:15]([C:16]([C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=4)=[C:8]2[C:7]1=[O:34])=[CH:14][C:13]([O:23][CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)=[CH:12][CH:11]=3)=O)C.[Cl-].[Na+]>CS(C)=O.O.C(OCC)(=O)C>[CH2:24]([O:23][C:13]1[CH:14]=[C:15]2[C:10](=[CH:11][CH:12]=1)[N:9]1[CH2:31][CH2:32][CH2:33][CH2:6][C:7](=[O:34])[C:8]1=[C:16]2[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

Komponenten

6

Edukt 2

HCID 5234Sodium ChlorideHCID 538189352-benzyloxy-7,8,9,10-tetrahydro-10-oxo-11-phenyl-6H-9-azepino[1,2-a]indole carboxylic acid ethylester

Produkt 1

HCID 20529096HCID 20529096, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 679Dimethyl SulfoxideLösungsmittelHCID 962WaterLösungsmittelHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

An amount of 2.8 g (6.17 m mole) of 2-benzyloxy-7,8,9,10-tetrahydro-10-oxo-11-phenyl-6H-9-azepino[1,2-a]indole carboxylic acid ethylester and 0.36 g (6.1 m mole) of sodium chloride were refluxed for four hours in 3.5 ml of dimethylsulfoxide and 0.35 ml of water. After cooling, the mixture was taken up in ethyl acetate, dried over sodium sulfate, suction filtered, and evaporated. The residue was triturated with petroleum ether and suction filtered.

Aufarbeitung

  1. temperatureAfter cooling
  2. dry with materialdried over sodium sulfate, suction
  3. filtrationfiltered
  4. customevaporated
  5. customThe residue was triturated with petroleum ether and suction
  6. filtrationfiltered

Quellen und Nachweise

ORD-Eintrag
ord-929c433145c4403784e80209aaed0953
Quelldatensatz
uspto-grants-1982_08
Patentnummer
US04343811

Notizen zur Reaktion

Wird geladen…