Potassium Permanganate → 1-Ethyl-5-butyryl-6-methyl-benzimidazole-2-carboxylic acid

Reaktionsgleichung

[CH2:1]([N:3]1[C:7]2[CH:8]=[C:9]([CH3:17])[C:10]([C:12](=[O:16])[CH2:13][CH2:14][CH3:15])=[CH:11][C:6]=2[N:5]=[C:4]1[CH2:18][OH:19])[CH3:2].[Mn]([O-])(=O)(=O)=[O:21].[K+]>>[CH2:1]([N:3]1[C:7]2[CH:8]=[C:9]([CH3:17])[C:10]([C:12](=[O:16])[CH2:13][CH2:14][CH3:15])=[CH:11][C:6]=2[N:5]=[C:4]1[C:18]([OH:21])=[O:19])[CH3:2]

Komponenten

Edukt 2

HCID 516875Potassium Permanganate

HCID 130606811-Ethyl-5-butyryl-6-methyl-benzimidazole-2-methanol

Produkt 1

HCID 128066581-Ethyl-5-butyryl-6-methyl-benzimidazole-2-carboxylic acid

Versuchsvorschrift

In a manner analogous to that described in Example 12, 5.2 g of 1-ethyl-5-butyryl-6-methyl-benzimidazole-2-methanol can be oxidised with 4.5 g of potassium permanganate to give 1-ethyl-5-butyryl-6-methyl-benzimidazole-2-carboxylic acid with a melting point >80° (decomposition).

Quellen und Nachweise

ORD-Eintrag: ord-5b4385fbd1a1402297d6cadd0c844878
Quelldatensatz: uspto-grants-1982_08
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US04344957

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