Water → 7-Phenyl-1H-indene

HRID 67814Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 67814
[C:1]1([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][CH2:10][CH:11]3O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(C)C=CC(S(O)(=O)=O)=CC=1.O>C1C=CC=CC=1>[C:1]1([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][CH:10]=[CH:11]3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Komponenten

5

Edukt 3

HCID 962WaterHCID 6101p-Toluenesulfonic acidHCID 129423854-Phenyl-2,3-dihydro-1H-inden-1-ol

Produkt 1

HCID 129423867-Phenyl-1H-indeneAusbeute 96,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel

Versuchsvorschrift

A stirred solution of 16.7 g (0.08 mole) of 4-phenyl-1-indanol and 0.1 g of p-toluenesulfonic acid in 180 ml of benzene was heated under reflux for one hour as by-product water was collected in a Dean-Stark trap. The reaction mixture was washed with two portions of 50 ml of a 5% aqueous solution of sodium bicarbonate, then with one portion of 50 ml of water. The organic phase was dried with magnesium sulfate, filtered, and the filtrate concentrated under reduced pressure, keeping the temperature under 50° C., to give 14.8 g of 7-phenyl-1H-indene. The nmr spectrum was consistent with the proposed structure.

Aufarbeitung

  1. customwas collected in a Dean-Stark trap
  2. washThe reaction mixture was washed with two portions of 50 ml of a 5% aqueous solution of sodium bicarbonate
  3. dry with materialThe organic phase was dried with magnesium sulfate
  4. filtrationfiltered
  5. concentrationthe filtrate concentrated under reduced pressure
  6. customunder 50° C.

Quellen und Nachweise

ORD-Eintrag
ord-750c27f0eb97440e9edc04a17018fbae
Quelldatensatz
uspto-grants-1982_08
Patentnummer
US04346251

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