Tetrahydrofuran → 3-[3-chloro-5-(2-methyl-2H-pyrazol-3-yl)-thiophen-2-yl]-8-(1-ethyl-propyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine
Reaktionsgleichung
[Br:17][c:18]1[cH:19][c:20]([Cl:39])[c:21](-[c:23]2[c:24]([CH3:38])[n:25][c:26]3[n:27]2[n:28][c:29]([CH3:37])[cH:30][c:31]3[CH:32]([CH2:33][CH3:34])[CH2:35][CH3:36])[s:22]1.[CH2:7]1[O:8][CH2:9][CH2:10][CH2:11]1.[CH3:12][CH2:13][CH2:14][CH2:15][Li:16].[CH3:1][n:2]1[cH:3][cH:4][cH:5][n:6]1.[CH3:40][CH2:41][O:42][C:43]([CH3:44])=[O:45]>>[CH3:1][n:2]1[c:3](-[c:18]2[cH:19][c:20]([Cl:39])[c:21](-[c:23]3[c:24]([CH3:38])[n:25][c:26]4[n:27]3[n:28][c:29]([CH3:37])[cH:30][c:31]4[CH:32]([CH2:33][CH3:34])[CH2:35][CH3:36])[s:22]2)[cH:4][cH:5][n:6]1
