HCID 178419031, Verbindung → HCID 178418735, Verbindung

HRID 6854

Reaktionsgleichung

Reaktionsgleichung von HRID 6854
C([O:8][C:9]1[CH:10]=[C:11]([NH:15][C:16]([NH2:18])=[NH:17])[CH:12]=[CH:13][CH:14]=1)C1C=CC=CC=1>CCO.[Pd]>[OH:8][C:9]1[CH:10]=[C:11]([NH:15][C:16]([NH2:18])=[NH:17])[CH:12]=[CH:13][CH:14]=1

Komponenten

4

Edukt 1

HCID 178419031HCID 178419031, Verbindung

Produkt 1

HCID 178418735HCID 178418735, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

To a solution of N-(3-benzyloxy-phenyl)guanidine (5.0 g, 20.6 mmol) in EtOH (150 mL) was added palladium on carbon (10%, wet, 50% water, 0.5 g)). The mixture was stirred under hydrogen atmosphere overnight. The reaction was filtered through a plug of celite and the filtrate concentrated in vacuo with toluene azeotroping to affored the desired material (2.83 g, 91%). 1H-NMR (MeOH-d4) δ 6.4–7 (m, 4H)

Aufarbeitung

  1. filtrationThe reaction was filtered through a plug of celite
  2. concentrationthe filtrate concentrated in vacuo with toluene azeotroping

Quellen und Nachweise

ORD-Eintrag
ord-1c2f6a5a2ec34decaf8e5a51310a14b6
Quelldatensatz
uspto-grants-2006_08
Patentnummer
US07084159B2

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