Methylhydrazine → (E)-(2,4,6-trifluorophenyl)methylidenehydrazine

HRID 69140

Reaktionsgleichung

Reaktionsgleichung von HRID 69140
[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[C:6]([F:11])[C:3]=1[CH:4]=O.C[NH:13][NH2:14]>CCOCC>[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[C:6]([F:11])[C:3]=1/[CH:4]=[N:13]/[NH2:14]

Komponenten

4

Edukt 2

HCID 6061MethylhydrazineHCID 5218452,4,6-Trifluorobenzaldehyde

Produkt 1

HCID 57917272(E)-(2,4,6-trifluorophenyl)methylidenehydrazine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

2,4,6-Trifluoro-benzaldehyde (x) (4.5 g, 27.3 mmol) was dissolved in Et2O, methylhydrazine was added (1.43 mL, 27.3 mmol) and the RM was stirred overnight. The solvent was evaporated and the solid residue was suspended in a mixture of pentane and EtOAc to afford after filtration the title compound as a bright yellow crystalline solid (tR 4.95 min (conditions 3), MH+=198.1).

Aufarbeitung

  1. customThe solvent was evaporated
  2. additionthe solid residue was suspended in a mixture of pentane and EtOAc
  3. customto afford
  4. filtrationafter filtration the title compound as a bright yellow crystalline solid (tR 4.95 min (conditions 3), MH+=198.1)

Quellen und Nachweise

ORD-Eintrag
ord-cd338e979c4d47d48408e78b4dc0922f
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08822468B2

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