(S)-5-dibenzylamino-1-methylpiperidin-2-one → HCID 28064098, Verbindung
Reaktionsgleichung
C([N:8](CC1C=CC=CC=1)[C@@H:9]1[CH2:14][N:13]([CH3:15])[C:12](=[O:16])[CH2:11][CH2:10]1)C1C=CC=CC=1>CO.[Pd]>[NH2:8][C@@H:9]1[CH2:14][N:13]([CH3:15])[C:12](=[O:16])[CH2:11][CH2:10]1Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
450 mg (S)-5-dibenzylamino-1-methyl-piperidin-2-one are suspended in 25 ml of methanol and hydrogenated with 150 mg Pd/C 10% under a pressure of 3 bar and at a temperature of 60° C. After 16 hours the catalyst is removed by suction filtering and the filtrate is evaporated to dryness. 190 mg of the product are obtained as an oil.
Aufarbeitung
- customAfter 16 hours the catalyst is removed by suction
- filtrationfiltering
- customthe filtrate is evaporated to dryness
Quellen und Nachweise
- ORD-Eintrag
- ord-361341bef66e4e7bbc5870aec89c9a28
- Quelldatensatz
- uspto-grants-2014_09
- Patentnummer
- US08822474B2
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