Pyridine → 1-(2-Ethyl-4-tetradecylphenoxy)-3-(triphenylmethoxy)-2-propanol

HRID 703326Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 703326
[CH2:1]([C:3]1[CH:14]=[C:13]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:12]=[CH:11][C:4]=1[O:5][CH2:6][CH:7]([OH:10])[CH2:8][OH:9])[CH3:2].[C:29](Cl)([C:42]1[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=1)([C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1)[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1.N1C=CC=CC=1>C(Cl)(Cl)Cl>[CH2:1]([C:3]1[CH:14]=[C:13]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:12]=[CH:11][C:4]=1[O:5][CH2:6][CH:7]([OH:10])[CH2:8][O:9][C:29]([C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)([C:42]1[CH:43]=[CH:44][CH:45]=[CH:46][CH:47]=1)[C:36]1[CH:37]=[CH:38][CH:39]=[CH:40][CH:41]=1)[CH3:2]

Komponenten

5

Edukt 3

HCID 1049PyridineHCID 6456Trityl chlorideHCID 142561973-(2-Ethyl-4-tetradecylphenoxy)-1,2-propanediol

Produkt 1

HCID 150302641-(2-Ethyl-4-tetradecylphenoxy)-3-(triphenylmethoxy)-2-propanolAusbeute 95,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Versuchsvorschrift

A mixture of 11.68 g of 3-(2-ethyl-4-tetradecylphenoxy)-1,2-propanediol, 14.95 g of trityl chloride and 40 ml pyridine was stirred for 72 hours, then diluted with chloroform, washed with two 100 ml portions of aqueous sodium bicarbonate, then water and dried. The solvents were evaporated under reduced pressure and the residue evaporated with toluene. This residue was then diluted with hexanes and the solid which formed collected giving 18 g of the desired compound.

Aufarbeitung

  1. washwashed with two 100 ml portions of aqueous sodium bicarbonate
  2. dry with materialwater and dried
  3. customThe solvents were evaporated under reduced pressure
  4. customthe residue evaporated with toluene
  5. additionThis residue was then diluted with hexanes
  6. customthe solid which formed
  7. customcollected

Quellen und Nachweise

ORD-Eintrag
ord-9db888636e084aab964259b3dc4ed0c6
Quelldatensatz
uspto-grants-1991_01
Patentnummer
US04981989

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