4-Methoxy cinnamic acid → 3-(p-Methoxyphenyl)propionic acid

HRID 704396

Reaktionsgleichung

Reaktionsgleichung von HRID 704396
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:6]([CH:7]=[CH:8][C:9]([OH:11])=[O:10])=[CH:5][CH:4]=1.[H][H]>CO.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][CH2:8][C:9]([OH:11])=[O:10])=[CH:12][CH:13]=1

Komponenten

5

Edukt 2

HCID 132454-Methoxy cinnamic acidHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 957503-(p-Methoxyphenyl)propionic acidAusbeute 100,5 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

10% Palladium-on-carbon (200 mg) was added to a solution of 5.34 g of 4-methoxycinnamic acid in methanol, and the mixture was stirred under hydrogen until hydrogen gas absorption ceased. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give 5.43 g of 3-(4-methoxyphenyl)propionic acid.

Aufarbeitung

  1. filtrationThe catalyst was filtered off
  2. concentrationthe filtrate was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-267d2b1845324df4bb8b26e892935043
Quelldatensatz
uspto-grants-1991_01
Patentnummer
US04987132

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