Diethyl Ether → Picolinohydrazide

Temperatur

80 °C

A mixture of ethyl pyridin-2-carboxylate (90 gm) and hydrazine (60 gm) in ethanol (400 ml) was stirred at 80° C. over a period of 4 h. Solvent was evaporated under vacuum to provide a crude mass. The crude mass was stirred with diethyl ether and the suspension was filtered and the wet cake washed with small quantity of ethanol (50 ml) to provide title compound in 76 gm quantity (93%) as a white solid.

1. customSolvent was evaporated under vacuum
2. customto provide a crude mass
3. filtrationthe suspension was filtered
4. washthe wet cake washed with small quantity of ethanol (50 ml)

ORD-Eintrag

ord-8bbad074dac646a2af175a410fab39b2

Quelldatensatz

uspto-grants-2015_11

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US09175031B2