Oxalyl chloride → Dimethyl-1,3-oxazole-5-carbonyl chloride

HRID 708787

Reaktionsgleichung

Reaktionsgleichung von HRID 708787
[CH3:1][C:2]1[O:3][C:4]([C:8]([OH:10])=O)=[C:5]([CH3:7])[N:6]=1.C(Cl)(=O)C([Cl:14])=O>C(Cl)Cl>[CH3:1][C:2]1[O:3][C:4]([C:8]([Cl:14])=[O:10])=[C:5]([CH3:7])[N:6]=1

Komponenten

4

Edukt 2

HCID 65578Oxalyl chlorideHCID 1132979Dimethyl-1,3-oxazole-5-carboxylic acid

Produkt 1

HCID 12336332Dimethyl-1,3-oxazole-5-carbonyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a stirring solution of 2,4-dimethyl-oxazole-5-carboxylic acid (30 mg) in DCM (2.0 mL), oxalyl chloride (3.0 eq) was added at room temperature. The reaction mixture was stirred for 30 minutes. Solvents were evaporated and dried under vacuo to afford 2,4-dimethyl-oxazole-5-carbonyl chloride.

Aufarbeitung

  1. customSolvents were evaporated
  2. customdried under vacuo

Quellen und Nachweise

ORD-Eintrag
ord-051aa11aea3d49acb73551ed03209563
Quelldatensatz
uspto-grants-2015_11
Patentnummer
US09175003B2

Verknüpfte Notizen

Wird geladen…