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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 711128Erstellt: 26. Oktober 2026

P-Coumaric Acid → HCID 178511829, Verbindung

https://huagongshe.com/reaction/711128

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktP-Coumaric AcidHCID 637542—
EduktSitagliptinHCID 4369359—
LösungsmittelTetrahydrofuranHCID 8028—
ProduktHCID 178511829HCID 178511829—

Reaktionsschritte

Sitagliptin free base (2.0 gms) and coumaric acid (0.80 gms) were dissolved in Tetrahydrofuran (100 ml) at 60° C. to 65° C. and the resultant solution left for slow solvent evaporation at room temperature for 18 hours. Precipitated solids were filtered and dried at 50° C. to 55° C. for 6 hours to obtain the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09181256B2
Quelldatensatzuspto-grants-2015_11
ORD IDord-fab031baf009491885169999dab0ca6a
Quellennotizuspto-grants-2015_11