反应详情

Sitagliptin free base (2.0 gms) and coumaric acid (0.80 gms) were dissolved in Tetrahydrofuran (100 ml) at 60° C. to 65° C. and the resultant solution left for slow solvent evaporation at room temperature for 18 hours. Precipitated solids were filtered and dried at 50° C. to 55° C. for 6 hours to obtain the title compound.

1. customPrecipitated solids
2. filtrationwere filtered
3. customdried at 50° C. to 55° C. for 6 hours