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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 711131Erstellt: 26. Oktober 2026

P-Coumaric Acid → HCID 178511829, Verbindung

https://huagongshe.com/reaction/711131

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktP-Coumaric AcidHCID 637542—
EduktSitagliptinHCID 4369359—
LösungsmittelEthyl AcetateHCID 8857—
ProduktHCID 178511829HCID 178511829—

Reaktionsschritte

Sitagliptin free base (2.0 gms) and coumaric acid (0.80 gms) were dissolved in ethyl acetate (32 ml) at 60° C. to 65° C. and the resultant reaction solution left for slow solvent evaporation at room temperature for 2 hours. Precipitated solids were filtered and dried at 50° C. to 55° C. for 6 hours to obtain the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09181256B2
Quelldatensatzuspto-grants-2015_11
ORD IDord-586d8063eff2411ab9aaf5dee10b9b55
Quellennotizuspto-grants-2015_11