反应详情

Sitagliptin free base (2.0 gms) and coumaric acid (0.80 gms) were dissolved in ethyl acetate (32 ml) at 60° C. to 65° C. and the resultant reaction solution left for slow solvent evaporation at room temperature for 2 hours. Precipitated solids were filtered and dried at 50° C. to 55° C. for 6 hours to obtain the title compound.

1. customthe resultant reaction solution
2. customPrecipitated solids
3. filtrationwere filtered
4. customdried at 50° C. to 55° C. for 6 hours