Water → 2-Nitro-6-(phenylthio)benzonitrile

HRID 711711

Reaktionsgleichung

Reaktionsgleichung von HRID 711711
[N+]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-:14])=[O:13])[C:5]=1[C:6]#[N:7])([O-])=O.C([O-])([O-])=O.[K+].[K+].[C:21]1([SH:27])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.O>CN(C=O)C>[N+:12]([C:8]1[CH:9]=[CH:10][CH:11]=[C:4]([S:27][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:5]=1[C:6]#[N:7])([O-:14])=[O:13]

Komponenten

6

Edukt 4

HCID 962WaterHCID 7969ThiophenolHCID 11430Potassium CarbonateHCID 520718Dinitrobenzonitrile

Produkt 1

HCID 151982412-Nitro-6-(phenylthio)benzonitrile

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Reaktionsbedingungen

Temperatur
0 °C

Versuchsvorschrift

To a mixture of 2,6-dinitrobenzonitrile (2.0 g, 10.36 mmol) and K2CO3 (1.43 g, 10.36 mmol) in 5 mL of anhydrous DMF was added PhSH (1.14 ml in 5 mL of DMF) dropwise under nitrogen at 0° C. After the completion of addition, the reaction mixture was stirred at 0° C. for 0.5 hr. Then the reaction mixture was poured into 50 mL of water, the resultant precipitation was collected by filtration, washed with water and dried in the air to give the title product.

Aufarbeitung

  1. additionAfter the completion of addition
  2. customthe resultant precipitation
  3. filtrationwas collected by filtration
  4. washwashed with water
  5. customdried in the air

Quellen und Nachweise

ORD-Eintrag
ord-103a63689a754403a715bb982d6222e8
Quelldatensatz
uspto-grants-2015_11
Patentnummer
US09181276B2

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