Ethylamine → (2,3,5-Tribromo-4-methoxy-phenyl)thiourea

HRID 712189Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 712189
[Br:1][C:2]1[C:7]([Br:8])=[C:6]([O:9][CH3:10])[C:5]([Br:11])=[CH:4][C:3]=1[NH:12][C:13]([NH:15]C(=O)OCC)=[S:14].C(N)C>>[Br:1][C:2]1[C:7]([Br:8])=[C:6]([O:9][CH3:10])[C:5]([Br:11])=[CH:4][C:3]=1[NH:12][C:13]([NH2:15])=[S:14]

Komponenten

3

Edukt 2

HCID 6341EthylamineHCID 86663965Ethyl N-[(2,3,5-tribromo-4-methoxy-phenyl)carbamothioyl]carbamate

Produkt 1

HCID 86663966(2,3,5-Tribromo-4-methoxy-phenyl)thiourea

Versuchsvorschrift

Ethyl N-[(2,3,5-tribromo-4-methoxy-phenyl)carbamothioyl]carbamate (500 mg, 1.02 mmol) was dissolved in ethylamine solution (5.09 mL, 10.18 mmol, 2 M in THF) and stirred at rt overnight. The mixture was concentrated to dryness under reduced pressure to give the desired compound as an off white solid. The mixture was used with no further purification in the next step. m/z: 416.83/418.84/420.83/422.83 [M+H]+.

Aufarbeitung

  1. concentrationThe mixture was concentrated to dryness under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-c09e4979c7b846c69b5eff87f87c6178
Quelldatensatz
uspto-grants-2015_11
Patentnummer
US09181234B2

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