Diisopropylethylamine → N-Cyclopropylmethyl-2-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-N-(4-oxo-3,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrimidin-2-ylmethyl)-acetamide

Reaktionsgleichung

[F:1][C:2]1[CH:19]=[CH:18][C:5]([C:6]([CH:8]2[CH2:13][CH2:12][N:11]([CH2:14][C:15]([OH:17])=O)[CH2:10][CH2:9]2)=[O:7])=[CH:4][CH:3]=1.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CCN(C(C)C)C(C)C.[CH:53]1([CH2:56][NH:57][CH2:58][C:59]2[NH:60][C:61](=[O:69])[C:62]3[CH2:68][O:67][CH2:66][CH2:65][C:63]=3[N:64]=2)[CH2:55][CH2:54]1>CN(C=O)C>[CH:53]1([CH2:56][N:57]([CH2:58][C:59]2[NH:60][C:61](=[O:69])[C:62]3[CH2:68][O:67][CH2:66][CH2:65][C:63]=3[N:64]=2)[C:15](=[O:17])[CH2:14][N:11]2[CH2:10][CH2:9][CH:8]([C:6](=[O:7])[C:5]3[CH:4]=[CH:3][C:2]([F:1])=[CH:19][CH:18]=3)[CH2:13][CH2:12]2)[CH2:55][CH2:54]1