Propylenediamine → HCID 178439575, Verbindung
Reaktionsgleichung
NCC(N)C.[NH2:6][CH2:7][CH:8]([NH2:12])[CH2:9][CH2:10][CH3:11].[C:13]([NH:21][C:22]1[CH:23]=[C:24]([CH:28]=[CH:29][N:30]=1)[C:25](O)=O)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:9]([CH:8]1[CH2:7][NH:6][C:25]([C:24]2[CH:28]=[CH:29][N:30]=[C:22]([NH:21][C:13](=[O:20])[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:23]=2)=[N:12]1)[CH2:10][CH3:11]Komponenten
4
Versuchsvorschrift
Following the procedure as described in EXAMPLE 9, making variations as required to replace 1,2-diaminopropane with 1,2-diaminopentane to react with 2-benzamidoisonicotinic acid, N-(4-(4-propyl-4,5-dihydro-1H-imidazol-2-yl)pyridin-2-yl)benzamide was obtained in 20% yield: MS (ES+) m/z 309.4 (M+1).
Quellen und Nachweise
- ORD-Eintrag