Benzaldehyde → 2-Methyl-N-(phenylmethylene)-2-propanamine

HRID 718733Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 718733
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:9]([NH2:13])([CH3:12])([CH3:11])[CH3:10]>>[CH:1](=[N:13][C:9]([CH3:12])([CH3:11])[CH3:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 240BenzaldehydeHCID 6385Tert-Butylamine

Produkt 1

HCID 1112402-Methyl-N-(phenylmethylene)-2-propanamineAusbeute 98 %

Reaktionsbedingungen

Temperatur
25 °C

Versuchsvorschrift

530.85 g (5.00 mol) of benzaldehyde was placed into a 2000 mL-volume flask equipped with a stirrer, a thermometer and a dropping funnel. Subsequently, 367.50 g (5.02 mol) of t-butyl amine was dropped into the flask in a water bath, while maintaining the solution temperature at 25° C. After the completion of the dropping, the mixture was reacted while stirring at 25° C. for 15 hours. After the completion of the reaction, the reaction mixture was subjected to separation, and the organic layer obtained was refluxed under reduced pressure (25° C., 13.3 Pa) for 2 hours, to provide 788.91 g of N-benzylidene-t-butyl amine. (Isolation yield; 98%)

Aufarbeitung

  1. customequipped with a stirrer
  2. customAfter the completion of the dropping, the mixture was reacted
  3. customAfter the completion of the reaction
  4. customthe reaction mixture was subjected to separation
  5. customthe organic layer obtained
  6. temperaturewas refluxed under reduced pressure (25° C., 13.3 Pa) for 2 hours

Quellen und Nachweise

ORD-Eintrag
ord-4e6a61839e904e18b373cc7793bf9706
Quelldatensatz
uspto-grants-2015_11
Patentnummer
US09194041B2

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