(S)-N-Cbz-1,1-diethoxypropan-2-amine → (2S)-1,1-Diethoxy-2-propanamine

To the solution of (S)-benzyl 1,1-diethoxypropan-2-ylcarbamate 844 mg (3.00 mmol) in methanol 50 ml, 5% palladium on carbon 30 mg was added and stirred at room temperature for 2 hours under hydrogen atmosphere. The reaction mixture was filtered on celite and washed with methanol 200 ml and the mother solution was concentrated in vacuo to obtain the title compound 442 mg (100%).

1. filtrationThe reaction mixture was filtered on celite
2. washwashed with methanol 200 ml
3. concentrationthe mother solution was concentrated in vacuo

ORD-Eintrag

ord-68a1c5da05ef41678ca657ec21b548d7

Quelldatensatz

uspto-grants-2015_11

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US09193734B2