Diethyl Oxalate → HCID 178488026, Verbindung
Reaktionsgleichung
Cl.Cl.[CH3:3][O:4][C:5]1[CH:6]=[C:7]([NH2:12])[C:8]([NH2:11])=[CH:9][CH:10]=1.[C:13](OCC)(=[O:19])[C:14](OCC)=[O:15].CCN(CC)CC>>[CH3:3][O:4][C:5]1[CH:6]=[C:7]2[C:8](=[CH:9][CH:10]=1)[N:11]=[C:14]([OH:15])[C:13]([OH:19])=[N:12]2Komponenten
4
Reaktionsbedingungen
- Temperatur
- 150 °C
Versuchsvorschrift
A suspension of 4-methoxybenzene-1,2-diamine dihydrochloride in diethyl oxalate (8 eq) was treated with Et3N (2 eq) and then heated at 150° C. for 2 hours. The mixture was cooled and filtered, and then the collected solid was washed with H2O and EtOH. The residue was dried to give the title compound (69%). MS (ES+) m/z 193 (M+H)+
Aufarbeitung
- temperatureThe mixture was cooled
- filtrationfiltered
- washthe collected solid was washed with H2O and EtOH
- customThe residue was dried
Quellen und Nachweise
- ORD-Eintrag
- ord-5b00df6953f24d92bf3225f4c5327b03
- Quelldatensatz
- uspto-grants-2014_09
- Patentnummer
- US08828930B2
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