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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 72242Erstellt: 25. Oktober 2026

1-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amine → 6-(tert-Butyl-diphenyl-silanyloxymethyl)-3-[4-(3-dimethylamino-pyrrolidin-1-yl)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one

https://huagongshe.com/reaction/72242

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amineHCID 21916591—
EduktHCID 131731827HCID 131731827—
Produkt6-(tert-Butyl-diphenyl-silanyloxymethyl)-3-[4-(3-dimethylamino-pyrrolidin-1-yl)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-oneHCID 131731826—

Reaktionsschritte

5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(dimethylamino-methyleneamino)-thiophene-2-carboxylic acid methyl ester was reacted with [1-(4-Amino-phenyl)-pyrrolidin-3-yl]-dimethyl-amine by method A1. The product with the molecular weight of 608.87 (C35H40N4O2SSi) was obtained in this way; MS (ESI): 609 (M+H+).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08828991B2
Quelldatensatzuspto-grants-2014_09
ORD IDord-00ebf7734d8f40c79d0e8437fbdbe257
Quellennotizuspto-grants-2014_09