Oxalyl chloride → 4-Methoxy-3-nitrobenzoyl chloride
Reaktionsgleichung
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].[CH3:7][O:8][C:9]1[CH:17]=[CH:16]C(C(O)=O)=[CH:11][C:10]=1[N+:18]([O-:20])=[O:19]>C1COCC1>[CH3:7][O:8][C:9]1[CH:17]=[CH:16][C:1]([C:2]([Cl:4])=[O:3])=[CH:11][C:10]=1[N+:18]([O-:20])=[O:19]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Oxalyl chloride (15.8 ml, 180 mmol) was added dropwise with stirring to a solution of 4-methoxy-3-nitrobenzoic acid (7.00 g, 36.00 mmol) in THF containing 10 μL DMF. After 1 h the solvent was removed under reduced pressure. The product was used directly in the next step.
Aufarbeitung
- customAfter 1 h the solvent was removed under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-78d80d48ad5e4408834a0a40c6d6770a
- Quelldatensatz
- uspto-grants-2006_11
- Patentnummer
- US07138425B2
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