Oxalyl chloride → HCID 86600622, Verbindung
Reaktionsgleichung
[CH2:1]([O:8][C:9]([C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[C:16](=[O:20])[N:15]([C:21]1[CH:22]=[C:23]([C:27]3[O:28][C:29]4[CH:35]=[C:34]([C:36](O)=[O:37])[CH:33]=[CH:32][C:30]=4[N:31]=3)[CH:24]=[CH:25][CH:26]=1)[C:14]2=[O:39])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(Cl)(=O)C([Cl:43])=O>>[CH2:1]([O:8][C:9]([C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[C:16](=[O:20])[N:15]([C:21]1[CH:26]=[CH:25][CH:24]=[C:23]([C:27]3[O:28][C:29]4[CH:35]=[C:34]([C:36]([Cl:43])=[O:37])[CH:33]=[CH:32][C:30]=4[N:31]=3)[CH:22]=1)[C:14]2=[O:39])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
Prepared by the method of Example 15a), from 2-[3-(5-benzyloxycarbonyl-1,3-dioxo-1,3-dihydro-isoindol-2-yl)phenyl]benzoxazole-6-carboxylic acid (2.50 g, 5.0 mmol) and oxalyl chloride (2.19 ml, 25 mmol) the subtitle compound was obtained. The product was used directly in the next step without purification.
Quellen und Nachweise
- ORD-Eintrag
- ord-a6216b38e55640fc9ddb9b2fa858486f
- Quelldatensatz
- uspto-grants-2006_11
- Patentnummer