tert-butyl (2RS,4SR,5RS)-1-{2-[3-(3-(benzyloxycarbonyl)phenyl)ureido]acetyl}-5-(2-fluorophenyl)-4-(phenylsulphonyl)pyrrolidine-2-carboxylate → (2S,4R,5R)-3-{3-[2-(4-benzyl-2-tert-butoxycarbonyl-5-phenyl-1-pyrrolidinyl)-2-oxoethyl]ureido}benzoic acid
Reaktionsgleichung
C([O:8][C:9]([C:11]1[CH:12]=[C:13]([NH:17][C:18](=[O:51])[NH:19][CH2:20][C:21]([N:23]2[CH:27]([C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=3F)[CH:26](S(C3C=CC=CC=3)(=O)=O)[CH2:25][CH:24]2[C:44]([O:46][C:47]([CH3:50])([CH3:49])[CH3:48])=[O:45])=[O:22])[CH:14]=[CH:15][CH:16]=1)=[O:10])C1C=CC=CC=1>C(O)C.[Pd]>[CH2:9]([C@H:26]1[C@H:27]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[N:23]([C:21](=[O:22])[CH2:20][NH:19][C:18](=[O:51])[NH:17][C:13]2[CH:12]=[C:11]([CH:16]=[CH:15][CH:14]=2)[C:9]([OH:8])=[O:10])[C@H:24]([C:44]([O:46][C:47]([CH3:48])([CH3:49])[CH3:50])=[O:45])[CH2:25]1)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1Komponenten
4
