Acetylpyrazine → Propanoic acid [1-(2-pyrazinyl)ethylidene]hydrazide

HRID 728545

Reaktionsgleichung

Reaktionsgleichung von HRID 728545
[C:1]([C:4]1[CH:9]=[N:8][CH:7]=[CH:6][N:5]=1)(=O)[CH3:2].[C:10]([NH:14][NH2:15])(=[O:13])[CH2:11][CH3:12]>C(O)C>[N:5]1[CH:6]=[CH:7][N:8]=[CH:9][C:4]=1[C:1](=[N:15][NH:14][C:10](=[O:13])[CH2:11][CH3:12])[CH3:2]

Komponenten

4

Edukt 2

HCID 30914AcetylpyrazineHCID 79890Propionylhydrazine

Produkt 1

HCID 54558617Propanoic acid [1-(2-pyrazinyl)ethylidene]hydrazideAusbeute 64,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 6.11 gm (0.05 mole) of 2-acetylpyrazine, 4.41 gm (0.05 mole) of propanoic acid hydrazide and 100 ml of absolute ethanol is refluxed 10 hr. The mixture is cooled. The white crystals which deposit are collected and dried to yield 6.17 gm (64%) of the title compound having a melting point of 181.3° C.

Aufarbeitung

  1. temperatureis refluxed 10 hr
  2. temperatureThe mixture is cooled
  3. customThe white crystals which deposit are collected
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-634a163bfca84dbcb8aac450056b0f69
Quelldatensatz
uspto-grants-1991_09
Patentnummer
US05049561

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