HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3,3-Dimethylbutanoyl chloride → 3,3-Dimethyl-1-(4-(2-methyl-4-(6-morpholinopyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)piperidin-1-yl)butan-1-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3,3-Dimethylbutanoyl chloride | HCID 81514 | — |
| Edukt | Cyclopentyl-{4-[4-(6-fluoro-pyrido[3,4-d]pyrimidin-4-ylamino)-2-methyl-phenoxy]-piperidin-1-yl}-methanone | HCID 69051928 | — |
| Edukt | [3-Methyl-4-(piperidin-4-yloxy)-phenyl]-(6-morpholin-4-yl-pyrido[3,4-d]pyrimidin-4-yl)-amine | HCID 69057517 | — |
| Produkt | 3,3-Dimethyl-1-(4-(2-methyl-4-(6-morpholinopyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)piperidin-1-yl)butan-1-one | HCID 44426279 | — |
Reaktionsschritte
The title compound was prepared from [3-Methyl-4-(piperidin-4-yloxy)-phenyl]-(6-morpholin-4-yl-pyrido[3,4-d]pyrimidin-4-yl)-amine and tert-butylacetyl chloride by a procedure analogous to the synthesis of Cyclopentyl-{4-[4-(6-fluoro-pyrido[3,4-d]pyrimidin-4-ylamino)-2-methyl-phenoxy]-piperidin-1-y}-methanone above.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07585869B2 |
| Quelldatensatz | uspto-grants-2009_09 |
| ORD ID | ord-b4e86cc2b87845a594f85e1362645728 |
| Quellennotiz | uspto-grants-2009_09 |