6-Bromo-N-methoxy-N-methylpicolinamide → (6-Bromo-pyridin-2-yl)-(4-chloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methanone

Beteiligte Stoffe

Reaktionsschritte

The title compound (34.0 g, 69%) was prepared from 5-Bromo-4-chloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine (35.8 g, 130.5 mmol) and 6-Bromo-pyridine-2-carboxylic acid methoxy-methyl-amide (32.0 g, 130.5 mmol) by procedures analogous to those described for the preparation (5-Bromo-pyridin-3-yl)-(4-chloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methanone. MS: 380.6 (MH+); HPLC Rf: 6.05 min. (HPLC method 4); HPLC purity: 100%.

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