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HRID736341

反应详情

EQUATION

反应方程式

HRID 736341 的结构方程式

REACTANTS

反应物

3
结构：CON(C)C(=O)c1cccc(Br)n1
HCID24730332

未命名化合物

结构：CC(C)n1cc(Br)c2c(Cl)ncnc21
HCID45789428

5-Bromo-4-chloro-7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine

C9H9BrClN3

结构：CC(C)n1cc(C(=O)c2cncc(Br)c2)c2c(Cl)ncnc21
HCID86603152

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)n1cc(C(=O)c2cccc(Br)n2)c2c(Cl)ncnc21
HCID86603155

未命名化合物

收率 69%

PROCEDURE

实验过程

The title compound (34.0 g, 69%) was prepared from 5-Bromo-4-chloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine (35.8 g, 130.5 mmol) and 6-Bromo-pyridine-2-carboxylic acid methoxy-methyl-amide (32.0 g, 130.5 mmol) by procedures analogous to those described for the preparation (5-Bromo-pyridin-3-yl)-(4-chloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methanone. MS: 380.6 (MH+); HPLC Rf: 6.05 min. (HPLC method 4); HPLC purity: 100%.