Diisopropylethylamine → 4-{(S)-2-(4-amino-3-chloro-5-trifluoromethyl-benzyl)-4-oxo-4-[4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidin-1-yl]-butyryl}-piperazin-1-sulphonic acid (1-methyl-piperidin-4-yl)-amide

Reaktionsgleichung

[NH2:1][C:2]1[C:33]([C:34]([F:37])([F:36])[F:35])=[CH:32][C:5]([CH2:6][C@@H:7]([CH2:11][C:12](=[O:31])[N:13]2[CH2:18][CH2:17][CH:16]([N:19]3[CH2:25][CH2:24][C:23]4[CH:26]=[CH:27][CH:28]=[CH:29][C:22]=4[NH:21][C:20]3=[O:30])[CH2:15][CH2:14]2)[C:8](O)=[O:9])=[CH:4][C:3]=1[Cl:38].CN(C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.[B-](F)(F)(F)F.C(N(C(C)C)C(C)C)C.[CH3:70][N:71]1[CH2:76][CH2:75][CH:74]([NH:77][S:78]([N:81]2[CH2:86][CH2:85][NH:84][CH2:83][CH2:82]2)(=[O:80])=[O:79])[CH2:73][CH2:72]1>C1COCC1.CCOC(C)=O.CN(C=O)C>[CH3:70][N:71]1[CH2:76][CH2:75][CH:74]([NH:77][S:78]([N:81]2[CH2:86][CH2:85][N:84]([C:8](=[O:9])[C@@H:7]([CH2:6][C:5]3[CH:32]=[C:33]([C:34]([F:36])([F:37])[F:35])[C:2]([NH2:1])=[C:3]([Cl:38])[CH:4]=3)[CH2:11][C:12](=[O:31])[N:13]3[CH2:18][CH2:17][CH:16]([N:19]4[CH2:25][CH2:24][C:23]5[CH:26]=[CH:27][CH:28]=[CH:29][C:22]=5[NH:21][C:20]4=[O:30])[CH2:15][CH2:14]3)[CH2:83][CH2:82]2)(=[O:80])=[O:79])[CH2:73][CH2:72]1