alpha-Hydroxyacetophenone → Flavonol

HRID 742080

Reaktionsgleichung

Reaktionsgleichung von HRID 742080
[C:1]1(C2C=CC=CC=2)[CH:6]=[CH:5][C:4]([CH:7]=[O:8])=[CH:3][CH:2]=1.[OH:15][CH2:16][C:17]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)=[O:18]>C(O)C.[OH-].[Na+]>[OH:15][C:16]1[C:7](=[O:8])[C:4]2[C:3](=[CH:2][CH:1]=[CH:6][CH:5]=2)[O:18][C:17]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Komponenten

5

Edukt 2

HCID 68490alpha-HydroxyacetophenoneHCID 76689(1,1'-Biphenyl)-4-carboxaldehyde

Produkt 1

HCID 11349Flavonol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittel2×HCID 14798Sodium HydroxideLösungsmittel2×

Versuchsvorschrift

180 mg of 4'-vinyl, 4-biphenyl aldehyde was mixed with 0.3 ml of 2-hydroxyacetophenone in 30 ml of ethanol. In a separate flask, 2.0 gms of NaOH was dissolved in 10 ml of aq. ethyl alcohol (50%). An NaOH solution was slowly added to the aldehyde solution. The resulting solution slowly changed its color from green to yellow to dark red. The rest of the reaction was carried out according to the method described in Example 1(b) above, producing 4'styryl, 3-hydroxyflavone.

Quellen und Nachweise

ORD-Eintrag
ord-21ed05cb9ada411cb768795976d60d3f
Quelldatensatz
uspto-grants-1996_09
Patentnummer
US05552551

Verknüpfte Notizen

Wird geladen…