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Hydroxylamine, O-(3-chloro-2-propenyl)-, hydrochloride → 2-(3-Chloroallyloxyaminobutylidene)-5-(3-methyl-4-ethyl-6-isobutoxytetrahydropyran-2-yl)-cyclohexane-1,3-dione

HRID 746124
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Druckvorschau

Reaktionsgleichung

Reaktionsgleichung von HRID 746124
[C:1]([CH:6]1[C:11](=[O:12])[CH2:10][CH:9]([CH:13]2[CH:18]([CH3:19])[CH:17]([CH2:20][CH3:21])[CH2:16][CH:15]([O:22][CH2:23][CH:24]([CH3:26])[CH3:25])[O:14]2)[CH2:8][C:7]1=[O:27])(=O)[CH2:2][CH2:3][CH3:4].Cl.[Cl:29][CH:30]=[CH:31][CH2:32][O:33][NH2:34]>C(O)C.C([O-])(=O)C.[Na+]>[Cl:29][CH:30]=[CH:31][CH2:32][O:33][NH:34][CH2:4][CH2:3][CH2:2][CH:1]=[C:6]1[C:7](=[O:27])[CH2:8][CH:9]([CH:13]2[CH:18]([CH3:19])[CH:17]([CH2:20][CH3:21])[CH2:16][CH:15]([O:22][CH2:23][CH:24]([CH3:26])[CH3:25])[O:14]2)[CH2:10][C:11]1=[O:12]
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Komponenten

5

Edukt 2

HCID 158057Hydroxylamine, O-(3-chloro-2-propenyl)-, hydrochlorideHCID 134214452-Butyryl-5-(3-methyl-4-ethyl-6-isobutoxytetrahydropyran-2-yl)-cyclohexane-1,3-dione

Produkt 1

HCID 543533332-(3-Chloroallyloxyaminobutylidene)-5-(3-methyl-4-ethyl-6-isobutoxytetrahydropyran-2-yl)-cyclohexane-1,3-dione

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittel
HCID 517045
Sodium Acetate
Lösungsmittel

Versuchsvorschrift

10.2 parts by weight of 2-butyryl-5-(3-methyl-4-ethyl-6-isobutoxytetrahydropyran-2-yl)-cyclohexane-1,3-dione were dissolved in 100 parts by volume of ethanol, and 2.42 parts by weight of sodium acetate and 3.86 parts by weight of O-(3-chloroallyl)-hydroxylamine hydrochloride were added. The mixture was stirred for several hours at room temperature and then poured into ice-water, and the resulting mixture was extracted with methylene chloride. The methylene chloride phase was evaporated off, leaving 11.1 parts by weight of 2-(3-chloroallyloxyaminobutylidene)-5-(3-methyl-4-ethyl-6-isobutoxytetrahydropyran-2-yl)-cyclohexane-1,3-dione as a yellow oil of refractive index nD22 1.5129.

Aufarbeitung

  1. additionwere added
  2. extractionthe resulting mixture was extracted with methylene chloride
  3. customThe methylene chloride phase was evaporated off

Quellen und Nachweise

ORD-Eintrag
ord-2679ef3b0ea54d12a1196452c5a1ec3e
Quelldatensatz
uspto-grants-1986_07
DOI
10.6084/m9.figshare.5104873.v1
Patentnummer
US04602935

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