N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-4-phenylbenzamide
Reaktionsgleichung
CNOC.O=C(O)c1ccc(-c2ccccc2)cc1.C1CCN(C1)C(=[N+]2CCCC2)ON3C4=CC=CC=C4N=N3.F[P-](F)(F)(F)(F)F.CN(C)C=O>>CON(C)C(=O)c1ccc(-c2ccccc2)cc1Komponenten
5
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Reaktionsbedingungen
- Temperatur
- 25 °C
Aufarbeitung
- addition150 uL of MeCN/H2O (1:1) mixed solvent was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
- addition150 uL of internal standard solution was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
- aliquot10 uL aliquot taken from reaction vials, and added to pre-filled wells in the transfer plate.
- addition380 uL MeCN solvent were added to the transfer plate
- aliquot20 uL taken from transfer plate to filter plate 1 for LCMS analysis
- addition180 uL MeCN added to filter plate 1 for LCMS analysis
- aliquot10 uL taken from transfer plate to filter plate 2 for TOF-DESI analysis
- addition190 uL MeCN added to filter plate 2 for TOF-DESI analysis
- customthe 96-well filter plates were centrifuged for 2.5 min at 3000 RPM
Quellen und Nachweise
- ORD-Eintrag
- ord-342dcfbd2d014f75822031492ce4e3eb
- Quelldatensatz
- AIChemEco amide coupling conditions 47k dataset
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